FANCJ REGULATES INTERSTRAND CROSSLINKER INDUCED CENTROSOME AMPLIFICATION THROUGH THE ACTIVATION OF POLO-LIKE KINASE 1

FancJ regulates interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1

Summary DNA damage response (DDR) and the centrosome cycle are two of the most critical processes for maintaining a stable genome in animals.Sporadic evidence suggests a connection between these two processes.Here, we report our findings that six Fanconi Anemia (FA) proteins, including FancI and FancJ, localize to the centrosome.Intriguingly, we fo

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Study of the magnitude of diabetes and its associated risk factors among the tuberculosis patients of Morang, Eastern Nepal

Abstract Background WHO addresses the infectious disease like Tuberculosis, and non- communicable disease like Diabetes among the top 10 causes of death worldwide, which collectively leads to increasing mortality and premature death especially in developing countries.Hence, the present study aims to assess the prevalence of diabetes and its associa

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Resilience and hopelessness mediate the relationship between benevolent childhood experiences and life satisfaction: evidence from a cross-cultural study

Abstract Background A ROSE PURE CASTILE SOAP growing body of literature focuses on the role of benevolent childhood experiences (BCEs) in predicting adulthood well-being, in addition to adverse childhood experiences (ACEs).However, cross-cultural differences are generally ignored in this endeavor.Hence, this study aimed to explore the role of BCEs

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Effect of organizational culture on organizational learning, employee engagement, and employee performance: Study of banking employees in Indonesia

Banking institutions are still interesting to study, as are the problems of their employees.If, in the past, organizational culture was an ideology that Stoppers was difficult to change, now it is possible to change it due to various economic, social, and political upheavals.This study aims to examine the effect of organizational culture on organiz

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